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- 抗原 See all Ataxin 3 (ATXN3) 抗体
- Ataxin 3 (ATXN3)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Ataxin 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- 1H9-2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product ATXN3 Primary Antibody
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anti-Ataxin 3 (ATXN3) (AA 1-364) antibody
ATXN3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyATXN3 适用: 人 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 1-288) antibodyATXN3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyKO Validated ATXN3 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 261-288) antibodyATXN3 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB23951 unconjugated
anti-Ataxin 3 (ATXN3) (AA 267-297), (Middle Region) antibodyATXN3 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyATXN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) antibodyATXN3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (AA 29-59) antibodyATXN3 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 3 (ATXN3) (N-Term) antibodyATXN3 适用: 人, 小鼠, 大鼠, 绵羊, Cow, 马, 兔, 犬, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Upon receipt, store undiluted between 2°C and 8°C.
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- 抗原
- Ataxin 3 (ATXN3)
- 别名
- Ataxin-3 (ATXN3 产品)
- 别名
- Mjd antibody, zgc:56323 antibody, ATXN3 antibody, at3 antibody, jos antibody, mjd antibody, atx3 antibody, mjd1 antibody, sca3 antibody, ataxin-3 antibody, MJD1 antibody, MGC83584 antibody, AT3 antibody, ATX3 antibody, JOS antibody, MJD antibody, SCA3 antibody, 2210008M02Rik antibody, AI463012 antibody, AI647473 antibody, Sca3 antibody, Rsca3 antibody, ataxin 3 antibody, ataxin 3 L homeolog antibody, ataxin-3 antibody, atxn3 antibody, ATXN3 antibody, atxn3.L antibody, MICPUN_104046 antibody, MICPUCDRAFT_46658 antibody, Atxn3 antibody
- 背景
- Ataxin-3 is an ubiquitously expressed protein which contains a poly-glutamine tract. Genetically abnormal expansion of the poly-glutamine repeats results in accumulation of ubiquitinated ataxin-3 protein aggregates and leads to a neurodegenerative disorder, Machado-Joseph disease (MJD). The protein has ubiquitin interacting motifs and a N-terminal Cysteine residue (C14) responsible for its deubiquitinating activity. Ataxin-3 binds and hydrolyzes polyubiquitinated proteins, and interacts with key proteasome components, such as p97/VCP and p45, indicating that Ataxin-3 may play functional roles in ubiquitin-proteasome system. The protein also act as a transcriptional repressor when interacting with transcriptional activators and coactivators.
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