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IRF1 抗体

IRF1 适用: 人 WB 宿主: 小鼠 Monoclonal 13H3A44 unconjugated
产品编号 ABIN2666257
发货至: 中国
  • 抗原 See all IRF1 抗体
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    适用
    • 86
    • 48
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    • 9
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    宿主
    • 90
    • 6
    • 1
    • 1
    小鼠
    克隆类型
    • 84
    • 14
    单克隆
    标记
    • 47
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    This IRF1 antibody is un-conjugated
    应用范围
    • 86
    • 33
    • 14
    • 12
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
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    Western Blotting (WB)
    纯化方法
    Affinity purified.
    克隆位点
    13H3A44
    亚型
    IgG2a kappa
    Top Product
    Discover our top product IRF1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store undiluted at 4°C.
  • 抗原
    IRF1 (Interferon Regulatory Factor 1 (IRF1))
    别名
    IRF1 (IRF1 产品)
    别名
    irf1 antibody, zgc:136945 antibody, IRF1 antibody, irf11 antibody, zgc:103566 antibody, IRF-1 antibody, MAR antibody, AU020929 antibody, Irf-1 antibody, interferon regulatory factor 1 antibody, interferon regulatory factor 1a antibody, interferon regulatory factor 1b antibody, IRF1 antibody, irf1a antibody, irf1b antibody, Irf1 antibody
    背景
    IRF1 is the first identified member of the interferon regulatory transcription factor family. Its expression is induced in response to pathogen infection or the stimulation of several cytokines, including type I and II IFN, IL-1, IL-6, and TNF-α. Upon stimulation, IRF1 is transcriptionally activated by STAT1 and NFκB transcription factors via the GAS (interferon-gamma-activated sequence) element in the IRF1 promoter. IRF1 plays important roles in mediating immune response during infection and development of T cells and NK cells. In addition to the immunomodulatory functions, IRF1 has also shown to be involved in the regulation of cell cycle progression, tumor suppression, and apoptosis. IRF1-mediated transcription can be repressed by IRF2 through competing for the same binding region on the promoters.
    途径
    Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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