IRF1 抗体
Quick Overview for IRF1 抗体 (ABIN2666257)
抗原
See all IRF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity purified.
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亚型
- IgG2a kappa
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anti-Interferon Regulatory Factor 1 (IRF1) (AA 44-319) antibody
IRF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) antibodyIRF1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 216-325) antibodyIRF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) antibodyIRF1 适用: 人, 小鼠 WB, IF (p), IHC (p), FACS, IF (cc) 宿主: 兔 Monoclonal 3G7 unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 1-325) antibodyIRF1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (N-Term) antibodyIRF1 适用: 人, 小鼠, 大鼠, 犬, Cow, 兔, 豚鼠, 绵羊, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) antibodyIRF1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (Internal Region) antibodyIRF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 11-276) antibodyIRF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interferon Regulatory Factor 1 (IRF1) (AA 1-325) antibodyIRF1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Upon receipt, store undiluted at 4°C.
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- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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别名
- IRF1
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背景
- IRF1 is the first identified member of the interferon regulatory transcription factor family. Its expression is induced in response to pathogen infection or the stimulation of several cytokines, including type I and II IFN, IL-1, IL-6, and TNF-α. Upon stimulation, IRF1 is transcriptionally activated by STAT1 and NFκB transcription factors via the GAS (interferon-gamma-activated sequence) element in the IRF1 promoter. IRF1 plays important roles in mediating immune response during infection and development of T cells and NK cells. In addition to the immunomodulatory functions, IRF1 has also shown to be involved in the regulation of cell cycle progression, tumor suppression, and apoptosis. IRF1-mediated transcription can be repressed by IRF2 through competing for the same binding region on the promoters.
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途径
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
抗原
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