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IL-21 抗体 (Biotin)

IL21 适用: 人, 小鼠 ICFC 宿主: 小鼠 Monoclonal 7H20-I19-M3 Biotin
产品编号 ABIN2666224
发货至: 中国
  • 抗原 See all IL-21 (IL21) 抗体
    IL-21 (IL21) (Interleukin 21 (IL21))
    适用
    • 81
    • 29
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 68
    • 16
    • 5
    • 4
    • 1
    小鼠
    克隆类型
    • 80
    • 14
    单克隆
    标记
    • 50
    • 12
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-21 antibody is conjugated to Biotin
    应用范围
    • 69
    • 57
    • 13
    • 12
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    交叉反应 (详细)
    Mouse* - weak affinity
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    克隆位点
    7H20-I19-M3
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL21 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide. Final antibody concentration is 0.5 mg/mL.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store frozen between 2°C and 8°C.
  • 抗原
    IL-21 (IL21) (Interleukin 21 (IL21))
    别名
    IL-21 (IL21 产品)
    别名
    IL-21 antibody, Za11 antibody, interleukin 21 antibody, IL21 antibody, Il21 antibody
    背景
    Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Recent studies have shown that IL-21 is also an autocrine cytokine that potently induces T(H)17 differentiation and suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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