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Acetylated Lysine 抗体 (acetylated)

FACS 宿主: 小鼠 Monoclonal 15G10 unconjugated
产品编号 ABIN2666081
发货至: 中国
  • 抗原 See all Acetylated Lysine products
    Acetylated Lysine
    抗原表位
    • 5
    • 1
    • 1
    acetylated
    适用
    请咨询
    宿主
    • 27
    • 13
    小鼠
    克隆类型
    • 26
    • 13
    单克隆
    标记
    • 19
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Acetylated Lysine antibody is un-conjugated
    应用范围
    • 39
    • 29
    • 25
    • 15
    • 11
    • 11
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    15G10
    亚型
    IgG2b kappa
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Upon receipt, store between 2°C and 8°C.
  • 抗原
    Acetylated Lysine
    Abstract
    Acetylated Lysine 产品
    别名
    C-K-RAS antibody, CFC2 antibody, K-RAS2A antibody, K-RAS2B antibody, K-RAS4A antibody, K-RAS4B antibody, KI-RAS antibody, KRAS1 antibody, KRAS2 antibody, NS antibody, NS3 antibody, RASK2 antibody, KRAS proto-oncogene, GTPase antibody, KRAS antibody
    物质类
    Chemical
    背景
    Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetyltransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins.
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