c-FOS 抗体
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- 抗原 See all c-FOS (c-Fos) 抗体
- c-FOS (c-Fos) (c-Fos)
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This c-FOS antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 交叉反应 (详细)
- Mouse (very weak)
- 纯化方法
- The antibody was purified by antigen-affinity chromatography.
- 克隆位点
- Poly6414
- 亚型
- IgG
- Top Product
- Discover our top product c-Fos Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Upon receipt, store at -20°C.
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- 抗原
- c-FOS (c-Fos) (c-Fos)
- 别名
- C-Fos (c-Fos 产品)
- 背景
- The c-fos protein, also known as FBJ murine viral (v-fos) oncogene homolog , is a 62 kD cellular oncogene. The c-fos protein contains a bZIP region with a DNA-binding domain and a leucine zipper domain. Together with c-jun, c-jun proteins form the heterodimeric AP-1 complex that binds to the TRE elements of cellular and viral genes including collagenase, interleukin 2, stromelysin, SV40 and polyoma among others. c-fos is expressed in a variety of normal adult tissues and has been implicated as a critical transcription factor for skeletal formation and maintenance. This transcription factor is modified by phosphorylation by a number of upstream kinases and has been shown to interact with a variety of other proteins involved in transcriptional regulation. c-fos has been implicated in the development of fibrous bone dysplasia and osteosarcoma. The c-fos protein has been shown to interact with a variety of other proteins including c-jun, TFIID, NCOA2, NFAT1, CHOP, ELK1, SRC1, and ETS1.
- 途径
- S100 Proteins
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