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c-FOS 抗体

This anti-c-FOS antibody is a 兔 多克隆 antibody detecting c-FOS in FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN2666052
发货至: 中国

Quick Overview for c-FOS 抗体 (ABIN2666052)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

Poly6414
  • 交叉反应 (详细)

    Mouse (very weak)

    纯化方法

    The antibody was purified by antigen-affinity chromatography.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store at -20°C.
  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    C-Fos

    背景

    The c-fos protein, also known as FBJ murine viral (v-fos) oncogene homolog , is a 62 kD cellular oncogene. The c-fos protein contains a bZIP region with a DNA-binding domain and a leucine zipper domain. Together with c-jun, c-jun proteins form the heterodimeric AP-1 complex that binds to the TRE elements of cellular and viral genes including collagenase, interleukin 2, stromelysin, SV40 and polyoma among others. c-fos is expressed in a variety of normal adult tissues and has been implicated as a critical transcription factor for skeletal formation and maintenance. This transcription factor is modified by phosphorylation by a number of upstream kinases and has been shown to interact with a variety of other proteins involved in transcriptional regulation. c-fos has been implicated in the development of fibrous bone dysplasia and osteosarcoma. The c-fos protein has been shown to interact with a variety of other proteins including c-jun, TFIID, NCOA2, NFAT1, CHOP, ELK1, SRC1, and ETS1.

    途径

    S100 Proteins
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