IFNAR1 抗体
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- 抗原 See all IFNAR1 抗体
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
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适用
- 小鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IFNAR1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 品牌
- Ultra-LEAF™
- 纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- 克隆位点
- MAR1-5A3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IFNAR1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 储存液
- Azide free
- 注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))
- 别名
- IFNAR-1 (IFNAR1 产品)
- 背景
- IFNAR-1, the type I IFN receptor subunit 1, is coexpressed with IFNAR-2 on nearly all cells and make up the heterodimeric receptor complex that binds to all type I IFNs (IFN-α/β). Type I IFNs are a group of structurally and functionally related cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor, and autoimmune responses. Ligand binding to the IFN-α/β receptor complex leads to the tyrosine phosphorylation and activation of IFNAR-1-associated Tyk2 and IFNAR-2-associated Jak1 signal transductions.
- 途径
- JAK/STAT Signaling, Hepatitis C
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