CD41, CD61 抗体
Quick Overview for CD41, CD61 抗体 (ABIN2665995)
抗原
See all CD41, CD61 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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品牌
- Ultra-LEAF™
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纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
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过滤
- 0.2 μm filtered
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内毒素水平
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
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亚型
- IgG2a kappa
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anti-CD41,CD61 antibody
适用: 人, Cow FACS, IP, ELISA, ICC 宿主: 小鼠 Monoclonal IVA30 unconjugated
anti-CD41,CD61 (PAC-1 epitope) antibody适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal PAC-1 unconjugated
anti-CD41,CD61 antibody适用: Cow, 绵羊, Cat, 犬, 山羊, 马, 兔 FACS, IP, ELISA 宿主: 小鼠 Monoclonal CO-35E4 unconjugated
anti-CD41,CD61 antibody (PE)适用: 小鸡 FACS 宿主: 小鼠 Monoclonal 11C3 PE
anti-CD41,CD61 (PAC-1 epitope) antibody (PE)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PE
anti-CD41,CD61 (PAC-1 epitope) antibody (PerCP)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 PerCP
anti-CD41,CD61 (PAC-1 epitope) antibody (FITC)适用: 人 FACS 宿主: 小鼠 Monoclonal PAC-1 FITC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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储存液
- Azide free
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注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD41, CD61 (CD41,CD61)
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别名
- CD41/CD61
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背景
- CD41/CD61, also known as gpIIb/IIIa, is a member of a family integrin receptors. This is a complex comprised by CD41 and CD61 through non-covalent association. CD41/CD61 is mainly expressed by platelets and megakaryocytes. The resting form of the CD41/CD61 complex is involved in platelet activation and aggregation by binding to immobilized fibrinogen. After activation, CD41/CD61 becomes a receptor for soluble fibrinogen and several other RGD-containing adhesive proteins such as von Willebrand Factor (vWF) and fibronectin. An absence or dysfunction of CD41/CD61 on the platelet surface results in an inherited bleeding disorder, called Glanzmann Thromsasthenia (GT). CD41/CD61 has been found on murine hematopoietic progenitor cells, indicating that this complex may play a role in regulating hematopoietic development.
抗原
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