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CD40 抗体

CD40 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal 1C10 unconjugated
产品编号 ABIN2665994
发货至: 中国
  • 抗原 See all CD40 抗体
    CD40
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    大鼠
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    单克隆
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    This CD40 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    品牌
    Ultra-LEAF™
    纯化方法
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    克隆位点
    1C10
    亚型
    IgG2a kappa
    Top Product
    Discover our top product CD40 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    储存液
    Azide free
    注意事项
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD40
    别名
    CD40 (CD40 产品)
    背景
    CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
    途径
    NF-kappaB Signaling, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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