TLR4 抗体
Quick Overview for TLR4 抗体 (ABIN2665977)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
品牌
- Ultra-LEAF™
-
交叉反应
- 豚鼠
-
纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
-
过滤
- 0.2 μm filtered
-
内毒素水平
-
Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
储存液
- Azide free
-
注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
-
储存条件
- 4 °C
-
储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
-
- TLR4 (Toll-Like Receptor 4 (TLR4))
-
别名
- CD284
-
背景
- Toll-like receptors are type I transmembrane signaling receptors. They are primordial pathogen-recognition proteins that function as sentinels for the innate immune system. TLR4, also known as CD284, is a 110 kD protein which is expressed on monocytes/macrophages, endothelial cells, and at low levels on B cells and granulocytes. In association with a secretory molecule, MD2, TLR4 has been recognized as critical for host recognition of bacterial LPS. HTA125 antibody is useful for flow cytometric analysis and is able to block LPS-induced cytokine production.
-
途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
-