PD-1 抗体
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- 抗原 See all PD-1 (PDCD1) 抗体
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This PD-1 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 品牌
- Ultra-LEAF™
- 纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- 克隆位点
- RMP1-14
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product PDCD1 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 储存液
- Azide free
- 注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- 别名
- CD279 (PDCD1 产品)
- 背景
- CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells).
- 途径
- Cancer Immune Checkpoints
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