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PD-1 抗体

PDCD1 适用: 小鼠 FACS, IHC, IF 宿主: 大鼠 Monoclonal RMP1-14 unconjugated
产品编号 ABIN2665971
发货至: 中国
  • 抗原 See all PD-1 (PDCD1) 抗体
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    适用
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    小鼠
    宿主
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    大鼠
    克隆类型
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    单克隆
    标记
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    This PD-1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    品牌
    Ultra-LEAF™
    纯化方法
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    克隆位点
    RMP1-14
    亚型
    IgG2a kappa
    Top Product
    Discover our top product PDCD1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    储存液
    Azide free
    注意事项
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    别名
    CD279 (PDCD1 产品)
    背景
    CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells).
    途径
    Cancer Immune Checkpoints
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