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PD-1 抗体

This anti-PD-1 antibody is a 大鼠 单克隆 antibody detecting PD-1 in FACS, IHC 和 IF. Suitable for 小鼠.
产品编号 ABIN2665971
发货至: 中国

Quick Overview for PD-1 抗体 (ABIN2665971)

抗原

See all PD-1 (PDCD1) 抗体
PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This PD-1 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

RMP1-14
  • 品牌

    Ultra-LEAF™

    纯化方法

    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.

    过滤

    0.2 μm filtered

    内毒素水平

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    储存液

    Azide free

    注意事项

    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

    别名

    CD279

    背景

    CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells).

    途径

    Cancer Immune Checkpoints
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