CD11b 抗体
-
- 抗原 See all CD11b (ITGAM) 抗体
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
-
适用
- 人, 小鼠
-
宿主
- 大鼠
-
克隆类型
- 单克隆
-
标记
- This CD11b antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 品牌
- Ultra-LEAF™
- 交叉反应
- Cynomolgus, 猕猴, Baboon, Chimpanzee, 兔
- 纯化方法
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- 过滤
- 0.2 μm filtered
- 内毒素水平
-
Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- 克隆位点
- M1-70
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product ITGAM Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 浓度
- 1.0 mg/mL
- 储存液
- Azide free
- 注意事项
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- 抗原
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- 别名
- CD11b (ITGAM 产品)
- 背景
- CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
- 途径
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
-