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KIT 抗体

KIT 适用: 小鼠 FACS, IHC, IF 宿主: 大鼠 Monoclonal ACK2 unconjugated
产品编号 ABIN2665946
发货至: 中国
  • 抗原 See all KIT 抗体
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    适用
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    大鼠
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    单克隆
    标记
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    This KIT antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    品牌
    Ultra-LEAF™
    纯化方法
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    过滤
    0.2 μm filtered
    内毒素水平

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    克隆位点
    ACK2
    亚型
    IgG2b kappa
    Top Product
    Discover our top product KIT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    储存液
    Azide free
    注意事项
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    别名
    CD117 (KIT 产品)
    背景
    CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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