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FLT4 抗体

This anti-FLT4 antibody is a 大鼠 单克隆 antibody detecting FLT4 in FACS. Suitable for 小鼠.
产品编号 ABIN2665456
发货至: 中国
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Room 801-803
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Quick Overview for FLT4 抗体 (ABIN2665456)

抗原

See all FLT4 抗体
FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

适用

  • 89
  • 51
  • 16
  • 12
小鼠

宿主

  • 72
  • 25
  • 8
  • 7
  • 2
大鼠

克隆类型

  • 73
  • 41
单克隆

标记

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  • 4
  • 1
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  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This FLT4 antibody is un-conjugated

应用范围

  • 56
  • 42
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  • 31
  • 14
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  • 9
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Flow Cytometry (FACS)

克隆位点

AFL4
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

    别名

    VEGFR-3

    背景

    VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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