TIGIT 抗体
Quick Overview for TIGIT 抗体 (ABIN2665413)
抗原
See all TIGIT 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG1 kappa
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anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 21-234) antibody
TIGIT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 22-141) antibodyTIGIT 适用: 人 IHC, ELISA, FACS, Coat, StM 宿主: 小鼠 Monoclonal TIGIT-3017 unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 22-141) antibodyTIGIT 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4C5B9 unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 28-246) antibodyTIGIT 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 22-141) antibodyTIGIT 适用: 人 IHC, ELISA, Coat, StM 宿主: 小鼠 Monoclonal TIGIT-3106 unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 28-227) antibodyTIGIT 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) antibodyTIGIT 适用: 小鼠 ELISA, FACS, BP 宿主: 兔 Chimeric 1B4 unconjugated Recombinant Antibody
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 22-141) antibodyTIGIT 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM178 unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 22-141) antibodyTIGIT 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT) (AA 12-142) antibodyTIGIT 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB55818 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains (TIGIT))
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别名
- TIGIT
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背景
- T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as V-set and transmembrane domain-containing protein 3 (Vstm3), is a 26 kD, type I transmembrane protein and member of the CD28 family. TIGIT is expressed on activated T cells, follicular T helper, memory, and regulatory T cells as well as on NK cells. Its ligands are PVR, PVRL2, PVRL3, CD155, and CD112. TIGIT is a negative regulator of NK and T cell activation. Engagement of TIGIT by dendritic cells results in their differentiation into a tolerogenic phenotype, with an increased secretion of IL-10 and a diminished production of IL-12. Mice deficient for TIGIT are more susceptible to autoimmune disease.
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途径
- Cancer Immune Checkpoints
抗原
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