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T-Bet 抗体

适用: 人, 小鼠 FACS 宿主: 小鼠 Monoclonal 4B10 unconjugated
产品编号 ABIN2665381
发货至: 中国
  • 抗原 See all T-Bet 抗体
    T-Bet
    适用
    • 58
    • 27
    • 23
    • 7
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 55
    • 6
    小鼠
    克隆类型
    • 55
    • 6
    单克隆
    标记
    • 31
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This T-Bet antibody is un-conjugated
    应用范围
    • 54
    • 23
    • 11
    • 8
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    4B10
    亚型
    IgG1 kappa
    Top Product
    Discover our top product T-Bet Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    T-Bet
    Abstract
    T-Bet 产品
    别名
    T-PET antibody, T-bet antibody, TBET antibody, TBLYM antibody, TBT1 antibody, Tbet antibody, Tblym antibody, T-box 21 antibody, TBX21 antibody, Tbx21 antibody
    背景
    T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and can be suppressed by addition of the Th2 cytokine IL-4 or neutralization of IL-12.
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