PAX9 抗体
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北京 101111
Quick Overview for PAX9 抗体 (ABIN2665320)
抗原
See all PAX9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG2a kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- PAX9 (Paired Box 9 (PAX9))
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别名
- PAX9
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背景
- PAX9 is a transcription factor belonging to the PAX family, which is composed of nine members defined by the presence of a paired box domain responsible for DNA binding. PAX9 is expressed at the E10 stage and downregulated at the bell stage. It is controlled by Fgf/Bmp signaling and plays an essential role in tooth development. PAX9 deficient mice fail to form teeth and show developmental arrest at the bud stage. In humans, heterozygous mutation in PAX9 is associate with tooth agenesis. These findings support the role of PAX9 in tooth development.
抗原
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