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Galectin 3 抗体 (AA 151-251)

The 小鼠 单克隆 anti-Galectin 3 antibody is suitable to detect Galectin 3 in samples from 人 和 小鼠. It has been validated for IP.
产品编号 ABIN2665254
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Galectin 3 抗体 (AA 151-251) (ABIN2665254)

抗原

See all Galectin 3 (LGALS3) 抗体
Galectin 3 (LGALS3)

适用

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人, 小鼠

宿主

  • 197
  • 53
  • 14
  • 3
  • 3
  • 1
小鼠

克隆类型

  • 157
  • 114
单克隆

标记

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This Galectin 3 antibody is un-conjugated

应用范围

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Immunoprecipitation (IP)

克隆位点

Gal397
  • 抗原表位

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    AA 151-251

    纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Galectin 3 (LGALS3)

    别名

    Mac-2

    物质类

    Chemical

    背景

    Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

    途径

    RTK signaling
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