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JAG2 抗体

JAG2 适用: 人 FACS 宿主: 小鼠 Monoclonal MHJ2-523 unconjugated
产品编号 ABIN2665211
发货至: 中国
  • 抗原 See all JAG2 抗体
    JAG2 (Jagged 2 (JAG2))
    适用
    • 49
    • 26
    • 23
    • 7
    • 5
    • 5
    • 2
    宿主
    • 45
    • 5
    • 1
    小鼠
    克隆类型
    • 44
    • 7
    单克隆
    标记
    • 24
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This JAG2 antibody is un-conjugated
    应用范围
    • 47
    • 17
    • 17
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    MHJ2-523
    亚型
    IgG1 kappa, IgG1
    Top Product
    Discover our top product JAG2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    JAG2 (Jagged 2 (JAG2))
    别名
    Jagged 2 (JAG2 产品)
    别名
    D12Ggc2e antibody, Serh antibody, mJagged2-1 antibody, sm antibody, HJ2 antibody, SER2 antibody, jag2 antibody, serB antibody, zgc:152855 antibody, jagged 2 antibody, jagged 2b antibody, JAG2 antibody, jag2 antibody, Jag2 antibody, jag2b antibody
    背景
    The binding of Notch ligands with their receptors results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus. This translocation triggers a series of signaling process. The Notch receptors and their ligands are highly conserved signaling molecules throughout development. They regulate cell fate decision for various cell developments, including myogenesis, neurogenesis, and lymphocyte development. There is growing evidence that signals transmitted through different Notch ligands can differentially affect target cells. The Jagged-2 is one of the several Notch ligands identified. It is a single pass transmembrane protein consisting of a large extracellular N-terminal which includes the DSL (Delta-Serrate-Lag-2) domain, followed by a tandem array of EGF-like repeats (ELRs) and cysteine-rich domain (CRD). Jagged 2 is expressed on lymphoma cells and some other tumor cells. Jagged-2 is reported to be essential for the regulation of spermatogenesis. Notch1/Jagged-2 signaling system plays an important role for male germ cells to differentiate, T cells and B cells to differentiate.
    途径
    Notch Signaling, Sensory Perception of Sound
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