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IRF6 抗体

This anti-IRF6 antibody is a 小鼠 单克隆 antibody detecting IRF6 in WB. Suitable for 人.
产品编号 ABIN2665207
发货至: 中国

Quick Overview for IRF6 抗体 (ABIN2665207)

抗原

See all IRF6 抗体
IRF6 (Interferon Regulatory Factor 6 (IRF6))

适用

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宿主

  • 65
  • 8
  • 1
小鼠

克隆类型

  • 59
  • 15
单克隆

标记

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This IRF6 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

14B2C16
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IRF6 (Interferon Regulatory Factor 6 (IRF6))

    别名

    IRF6

    背景

    IRF6 is a member of the IRF family of transcription factors, which are based on the presence of the conserved IRF tryptophan pentad repeat DNA-binding domain. Unlike other IRF transcription factors, IRF6 is not involved in the expression of interferon genes and doesn't seem to be involved in innate immunity. Data suggests that IRF6 is necessary for appropriate epidermal differentiation and development. Mutations of IRF6 are associated with human craniofacial developmental defects such as cleft lip, palate, tooth agenesis, Van der Woude syndrome, and popliteal pterygium syndrome. IRF6-deficient mice display severe morphological defects in skin and limbs, and result in perinatal lethality as well.
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