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IL-34 抗体

This 大鼠 单克隆 antibody specifically detects IL-34 in IP. It exhibits reactivity toward 小鼠.
产品编号 ABIN2665167
发货至: 中国
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Quick Overview for IL-34 抗体 (ABIN2665167)

抗原

See all IL-34 (IL34) 抗体
IL-34 (IL34) (Interleukin 34 (IL34))

适用

  • 44
  • 30
  • 7
  • 1
  • 1
小鼠

宿主

  • 50
  • 17
  • 4
  • 1
大鼠

克隆类型

  • 54
  • 18
单克隆

标记

  • 35
  • 9
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL-34 antibody is un-conjugated

应用范围

  • 47
  • 29
  • 17
  • 13
  • 13
  • 10
  • 8
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 2
Immunoprecipitation (IP)

克隆位点

C051-77
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2c
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL-34 (IL34) (Interleukin 34 (IL34))

    别名

    IL-34

    背景

    IL-34 is a glycoprotein that plays important roles in the proliferation, survival, and differentiation of monocytes and macrophages. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage development. IL-34 also promotes inflammatory processes and regulates osteoclast proliferation, differentiation, and bone reabsorption.

    途径

    RTK signaling
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