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EPO 抗体

This anti-EPO antibody is a 大鼠 单克隆 antibody detecting EPO in FACS. Suitable for 小鼠.
产品编号 ABIN2664956
发货至: 中国

Quick Overview for EPO 抗体 (ABIN2664956)

抗原

See all EPO 抗体
EPO (Erythropoietin (EPO))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This EPO antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

M029F6
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG2b
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    EPO (Erythropoietin (EPO))

    别名

    EPO

    物质类

    Hormone

    背景

    EPO is a glycoprotein that is glycosylated up to 40-60 % , which causes its molecular weight to vary from 30-34 kD depending on the carbohydrate percentage. Hypoxia induces erythropoiesis, and hypoxia inducible factor (HIF) is directly involved in EPO expression. HIF-Prolyl hydroxylase (HIF-PH) is a sensor of levels of iron, oxygen, and metabolic activity. High levels of HIF protein induces EPO production in the kidneys and liver, and mobilizes iron to support erythropoiesis. EPO has been used in the treatment of anemia associated with chronic kidney disease, treatment of cancer patients on chemotherapy, and antiviral HIV therapy.

    途径

    JAK/STAT Signaling, Hormone Activity, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
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