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CD80 抗体

CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal 2D10 unconjugated
产品编号 ABIN2664832
发货至: 中国
  • 抗原 See all CD80 抗体
    CD80
    适用
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    宿主
    • 92
    • 72
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    • 1
    小鼠
    克隆类型
    • 135
    • 79
    • 2
    单克隆
    标记
    • 91
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    This CD80 antibody is un-conjugated
    应用范围
    • 126
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    Flow Cytometry (FACS)
    交叉反应
    猕猴
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    2D10
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD80 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CD80
    别名
    CD80 (CD80 产品)
    背景
    CD80, also known as B7-1, B7, and BB1, is a 60 kD single chain type I glycoprotein belonging to the immunoglobulin superfamily. CD80 is expressed on activated B and T cells, macrophages, and dendritic cells. CD80 binds to CD28 and CD152 (CTLA-4). Along with CD86, CD80 plays a critical role in regulation of T cell activation. The interaction of CD80 with CD28 provides a potent costimulatory signal for T cell activation through the CD3 complex, while its interaction with CTLA-4 provides an inhibitory signal for T cell activation.
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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