CD8 抗体
Quick Overview for CD8 抗体 (ABIN2664826)
抗原
See all CD8 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops), Chimpanzee, Cynomolgus, Pigtailed Macaque, 猕猴, Sooty mangabey (Cercocebus atys), Green Monkey (Chlorocebus sabaeus)
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纯化方法
- The antibody was purified by affinity chromatography.
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亚型
- IgG1 kappa
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- CD8
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别名
- CD8
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背景
- CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.
抗原
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