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Integrin beta 3 抗体

ITGB3 适用: 人 FACS 宿主: 小鼠 Monoclonal VI-PL2 unconjugated
产品编号 ABIN2664787
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    宿主
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    小鼠
    克隆类型
    • 115
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    单克隆
    标记
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    This Integrin beta 3 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    交叉反应
    Baboon, 猕猴, Cynomolgus
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    VI-PL2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    CD61 (ITGB3 产品)
    背景
    CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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