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TLR1 抗体

TLR1 适用: 人 FACS 宿主: 小鼠 Monoclonal TLR1-136 unconjugated
产品编号 ABIN2664500
发货至: 中国
  • 抗原 See all TLR1 抗体
    TLR1 (Toll-Like Receptor 1 (TLR1))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This TLR1 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    TLR1-136
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TLR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    TLR1 (Toll-Like Receptor 1 (TLR1))
    别名
    CD281 (TLR1 产品)
    背景
    Toll-like receptors (TLRs) are type I transmembrane signaling receptors characterized by containing leucine-rich repeats (LRR) extracellular domain and IL-1 receptor like intracellular domain. TLRs are responsible for recognizing pathogen-associated molecule patterns (PAMPs). They are primary sensors of both innate and adaptive immune systems. To date a total of 12 TLRs have been indentified. Toll-like receptor 1 (TLR1), known as CD281, is expressed on monocytes/macrophages, dendritic cells, and granulocytes and some lymphocytes at low levels. By association with TLR2, TLR1 is a coreceptor involved in the response to diverse set of pathogens, such as triacylated lipopeptidess (but not diacylated lipopeptides), peptidoglycans, lipoteichoic acid.
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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