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- 抗原 See all CD276 抗体
- CD276
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适用
- 人, 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD276 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 交叉反应
- 人
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- MIH35
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CD276 Primary Antibody
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anti-CD276 (CD276) (AA 29-466) antibody
CD276 适用: 人 ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 8C1C2 unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-213) antibodyCD276 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) antibodyCD276 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 6A1 unconjugated
anti-CD276 (CD276) (AA 493-522), (C-Term) antibodyCD276 适用: 人 WB, FACS, IHC (p), IF 宿主: 兔 Polyclonal RB31111 unconjugated
anti-CD276 (CD276) (AA 237-358) antibodyCD276 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E12 unconjugated
anti-CD276 (CD276) (AA 100-200) antibodyCD276 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 101-200) antibodyCD276 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD276 (CD276) (AA 47-219) antibodyCD276 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-CD276 (CD276) (AA 29-200) antibodyCD276 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CD276
- 别名
- CD276 (CD276 产品)
- 背景
- B7-H3 is a type I transmembrane protein belonging to the B7 family of co-stimulatory proteins. B7-H3 is mostly expressed on professional APCs including B cells, macrophages, and dendritic cells at low level. It is detected on various human and murine tumor cells, nasal and airway epithelial cells. Its expression on dendritic cells appears to be up-regulated by LPS. Initial studies have shown that B7-H3 provides a stimulatory signal to T cells. However, recent studies suggest a negative regulatory role for B7-H3 in T cell responses. Mouse B7-H3 protein inhibited T cell activation and effector cytokine production. Thus, the immunological function of B7-H3 remains unclear. B7-H3 is involved in the suppression of Th1-mediated immune responses and plays an important role in the development of pathogenic Th2 cells in a murine asthma model. Monoclonal antibody against B7-H3 enhances T cell proliferation in vitro and leads to exacerbated EAE in vivo. It was reported recently that the Triggering Receptor Expressed on Myeloid cells (TREM)-like Transcript 2 (TLT-2, TREML2) is a receptor for B7-H3 in mice. It remains controversial. Further studies are needed to identify the receptor of B7-H3.
- 途径
- Cancer Immune Checkpoints
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