CCR4 抗体
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- 抗原 See all CCR4 抗体
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
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适用
- 小鼠
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宿主
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Armenian Hamster
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克隆类型
- 单克隆
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标记
- This CCR4 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS)
- 纯化方法
- The antibody was purified by affinity chromatography.
- 克隆位点
- 2G12
- 亚型
- IgG
- Top Product
- Discover our top product CCR4 Primary Antibody
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anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 201-300) antibody
CCR4 适用: 人, 大鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) antibodyCCR4 适用: 人 FACS, cELISA 宿主: 小鼠 Monoclonal KH-4F5 unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 适用: 人, 猴 ELISA, WB, FACS, IHC, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 309-360) antibodyCCR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (Extracellular Domain) antibodyCCR4 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (N-Term) antibodyCCR4 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 180-229) antibodyCCR4 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 17-39) antibodyCCR4 适用: 人 ELISA, WB, FACS, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 4 (CCR4) (AA 337-351) antibodyCCR4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))
- 别名
- CD194 (CCR4 产品)
- 别名
- CC-CKR-4 antibody, CD194 antibody, CKR4 antibody, CMKBR4 antibody, ChemR13 antibody, HGCN:14099 antibody, K5-5 antibody, Ccr4 antibody, C-C CKR-4 antibody, CHEMR1 antibody, Cmkbr4 antibody, LESTR antibody, Sdf1r antibody, C-C motif chemokine receptor 4 antibody, chemokine (C-C motif) receptor 4 antibody, CCR4 antibody, Ccr4 antibody
- 背景
- Mouse CCR4 cDNA contains 1531 bp, and encodes a protein of 360 amino acids that is 85 % identical to human CCR4. CCR4 binds CCL17 (TARG) and CCL22 (MDC). Naive T cells, bearing receptors for cutaneous antigens, become activated in skin-draining lymph nodes and express cutaneous lymphocyte antigen (CLA), which confers to these cells the capacity to migrate into the skin to exert their normal effector functions (1). CCR4 and CCR10 play an important role in the ligand-mediated recruitment of T cells into the skin in mice and humans, specifically with regards to tethering, firm adhesion, and subsequent extravasation to the site of injury (2,3). CCR4 is expressed in cutaneous regulatory T cells (Tregs). These cells are crucial for the induction and maintenance of self-tolerance and are present in peripheral tissues such as skin and gut under normal, noninflamed conditions (4).In addition, recruitment of Foxp3+ T regulatory cells mediating allograft tolerance depends on the CCR4 chemokine receptor and its ligand CCL22 (5).
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