电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

SIGLEC5 抗体

SIGLEC5 适用: 人 ICFC 宿主: 小鼠 Monoclonal 1A5 unconjugated
产品编号 ABIN2664288
发货至: 中国
  • 抗原 See all SIGLEC5 抗体
    SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
    适用
    • 65
    • 28
    • 4
    宿主
    • 59
    • 6
    • 3
    小鼠
    克隆类型
    • 59
    • 9
    单克隆
    标记
    • 25
    • 11
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC5 antibody is un-conjugated
    应用范围
    • 55
    • 35
    • 16
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    交叉反应
    Chimpanzee, Bonobo, Gorilla
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    1A5
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SIGLEC5 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    SIGLEC5 (Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
    别名
    CD170 (SIGLEC5 产品)
    别名
    CD170 antibody, CD33L2 antibody, OB-BP2 antibody, OBBP2 antibody, SIGLEC-5 antibody, sialic acid binding Ig like lectin 5 antibody, sialic acid-binding Ig-like lectin 5 antibody, sialic acid binding Ig-like lectin 5 antibody, SIGLEC5 antibody, LOC100597560 antibody, Siglec5 antibody
    背景
    CD170, also known as Siglec-5, is a single pass transmembrane protein member of the immunoglobulin superfamily. On the cell surface, CD170 forms a 140 kD dimer. The cytoplasmic domain of Siglec-5 contains two ITIM motifs that recruit the tyrosine-phosphatases SHP-1 and SHP-2 after tyrosine-phosphorylation, which in turn results in the inhibition of cell signaling. Siglec-5 is expressed by granulocytes, monocytes/macrophages, subsets of lymphocytes, and a subset of activated dendritic cells. Siglec-5 binds α2,3- and α2,6-linked sialic acid as well as glycophorin A, and is involved in cell adhesion.
You are here:
客服