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CCRL1 抗体

CCRL1 适用: 人 ELISA, IHC, ICFC 宿主: 小鼠 Monoclonal 13E11 unconjugated
产品编号 ABIN2664103
发货至: 中国
  • 抗原 See all CCRL1 抗体
    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
    适用
    • 17
    • 10
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    • 3
    • 3
    • 2
    • 1
    • 1
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    • 1
    宿主
    • 16
    • 1
    小鼠
    克隆类型
    • 17
    单克隆
    标记
    • 17
    This CCRL1 antibody is un-conjugated
    应用范围
    • 13
    • 9
    • 8
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Intracellular Flow Cytometry (ICFC)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    13E11
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CCRL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
    别名
    CCX-CKR (CCRL1 产品)
    别名
    CC-CKR-11 antibody, CCBP2 antibody, CCR-11 antibody, CCR10 antibody, CCR11 antibody, CCRL1 antibody, CCX CKR antibody, CCX-CKR antibody, CKR-11 antibody, PPR1 antibody, VSHK1 antibody, A630091E18Rik antibody, CCX-CKR1 antibody, Ccrl1 antibody, Cmkbrl1 antibody, atypical chemokine receptor 4 antibody, chemokine (C-C motif) receptor-like 1 antibody, Chemokine receptor-like 1 antibody, chemerin chemokine-like receptor 1 antibody, ACKR4 antibody, Ackr4 antibody, CCRL1 antibody, cml1 antibody, CMKLR1 antibody
    背景
    Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seven transmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding by CCX-CKR causes its internalization, reducing levels of available chemokine, and thus regulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromal cells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). A low CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancer patients.
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