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C5AR1 抗体

This anti-C5AR1 antibody is a 小鼠 单克隆 antibody detecting C5AR1 in FACS, IF 和 IP. Suitable for 人.
产品编号 ABIN2664087
发货至: 中国

Quick Overview for C5AR1 抗体 (ABIN2664087)

抗原

See all C5AR1 抗体
C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

适用

  • 100
  • 28
  • 14
  • 12
  • 12
  • 8
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
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  • 1

宿主

  • 72
  • 27
  • 21
  • 2
  • 1
  • 1
小鼠

克隆类型

  • 72
  • 47
  • 2
单克隆

标记

  • 70
  • 10
  • 9
  • 8
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This C5AR1 antibody is un-conjugated

应用范围

  • 72
  • 62
  • 40
  • 21
  • 17
  • 14
  • 13
  • 13
  • 10
  • 8
  • 8
  • 5
  • 4
  • 2
  • 1
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Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

克隆位点

C17-5
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

    别名

    C5a/C5a

    背景

    C5, complement component 5, is a protein involved in the complement system. It is cleaved into C5a and C5b by the C3/C5 convertase. The smaller fragment C5a is an anaphylatoxin and is released into the fluid surroundings. C5a is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C5a also stimulates the locomotion of polymorphonuclear leukocytes (chemokinesis) and direct their migration toward sites of inflammation (chemotaxis). C5a contains 74 amino acids and is rapidly metabolised by a serum enzyme, carboxypeptidase B to a 73 amino acid form, C5a des-Arg. The major fragment C5b binds to the membrane initiating the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex.

    途径

    Complement System
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