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C3a 抗体

C3a 适用: 人 IP, ELISA, FACS 宿主: 小鼠 Monoclonal K13-16 unconjugated
产品编号 ABIN2664084
发货至: 中国
  • 抗原 See all C3a 抗体
    C3a (Complement Fragment 3a (C3a))
    适用
    • 12
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 7
    • 6
    • 4
    小鼠
    克隆类型
    • 10
    • 7
    单克隆
    标记
    • 13
    • 2
    • 1
    • 1
    This C3a antibody is un-conjugated
    应用范围
    • 15
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunoprecipitation (IP), ELISA, Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    K13-16
    亚型
    IgG1 kappa
    Top Product
    Discover our top product C3a Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    C3a (Complement Fragment 3a (C3a))
    别名
    C3a/C3a/C3 (C3a 产品)
    别名
    AHUS5 antibody, ARMD9 antibody, ASP antibody, C3a antibody, C3b antibody, CPAMD1 antibody, AI255234 antibody, HSE-MSF antibody, Plp antibody, C3d antibody, complement C3 antibody, complement component 3 antibody, C3 antibody
    背景
    C3, complement component 3, is a 195 kD glycoprotein heterodimer that is linked by disulfide bonds. It is the fourth complement component to react in the classical pathway and it is also a reactant in the alternative complement pathway. C3 convertase splits C3 into C3b and C3a. C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Macrophages and neutrophils have receptors for C3b. C3a is released into the surrounding fluids. It can bind to receptors on basophils and mast cells triggering them to release their vasoactive contents (e.g., histamine). Because of the role of these materials in anaphylaxis, C3a is called an anaphylatoxin. In blood, the C3a fragment is rapidly desarginated by serum carboxypeptidase N enzyme to generate C3a desArg. Both C3a and C3a desArg are not glycosylated.
    途径
    Complement System
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