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PRDM1 抗体

PRDM1 适用: 人 FACS 宿主: 小鼠 Monoclonal ROS195G unconjugated
产品编号 ABIN2664076
发货至: 中国
  • 抗原 See all PRDM1 抗体
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    适用
    • 60
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    • 3
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    • 1
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    宿主
    • 37
    • 24
    • 3
    • 1
    小鼠
    克隆类型
    • 42
    • 23
    单克隆
    标记
    • 46
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    • 2
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    • 1
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    This PRDM1 antibody is un-conjugated
    应用范围
    • 49
    • 33
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    • 3
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    Flow Cytometry (FACS)
    交叉反应
    小鼠
    纯化方法
    The antibody was purified by affinity chromatography.
    克隆位点
    ROS195G
    亚型
    IgG1
    Top Product
    Discover our top product PRDM1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
    别名
    Blimp-1 (PRDM1 产品)
    背景
    Blimp-1 is a 98 Kd protein containing five Kuppel-type zinc finger domains that confer sequence specific DNA binding. It has been postulated to be a master regulator of terminal B cell differentiation. In the BCL-1 lymphoma model of differentiation from mature B cells to plasma cells, ectopic expression of Blimp-1 is sufficient to cause terminal differentiation manifested by loss of surface immunoglobulin, IgM secretion, expression of syndecan-1 and cessation of cell division. Recently, it is reported that Blimp-1 is also involved in T cell differentiation and T cell homeostasis and suppression of IL-2 production.
    途径
    Regulation of Muscle Cell Differentiation
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