JAG2 抗体 (PE)
Quick Overview for JAG2 抗体 (PE) (ABIN2663815)
抗原
See all JAG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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亚型
- IgG1 kappa, IgG1
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anti-Jagged 2 (JAG2) (AA 714-981) antibody
JAG2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 709-941) antibodyJAG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 121-210) antibodyJAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Jagged 2 (JAG2) (AA 24-200) antibodyJAG2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) antibodyJAG2 适用: 人, 小鼠, 大鼠 FACS, IHC (fro) 宿主: 仓鼠 Monoclonal HMJ2-1 unconjugated
anti-Jagged 2 (JAG2) antibodyJAG2 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 121-210) antibodyJAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Jagged 2 (JAG2) (N-Term) antibodyJAG2 适用: 人, 小鼠, 大鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jagged 2 (JAG2) (AA 1209-1238), (C-Term) antibodyJAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB1913-1914 unconjugated
anti-Jagged 2 (JAG2) (AA 150-200) antibodyJAG2 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- JAG2 (Jagged 2 (JAG2))
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别名
- Jagged 2
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背景
- The binding of Notch ligands with their receptors results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus. This translocation triggers a series of signaling process. The Notch receptors and their ligands are highly conserved signaling molecules throughout development. They regulate cell fate decision for various cell developments, including myogenesis, neurogenesis, and lymphocyte development. There is growing evidence that signals transmitted through different Notch ligands can differentially affect target cells. The Jagged-2 is one of the several Notch ligands identified. It is a single pass transmembrane protein consisting of a large extracellular N-terminal which includes the DSL (Delta-Serrate-Lag-2) domain, followed by a tandem array of EGF-like repeats (ELRs) and cysteine-rich domain (CRD). Jagged 2 is expressed on lymphoma cells and some other tumor cells. Jagged-2 is reported to be essential for the regulation of spermatogenesis. Notch1/Jagged-2 signaling system plays an important role for male germ cells to differentiate, T cells and B cells to differentiate.
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途径
- Notch Signaling, Sensory Perception of Sound
抗原
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