Integrin beta 7 抗体 (PE)
Quick Overview for Integrin beta 7 抗体 (PE) (ABIN2663810)
抗原
See all Integrin beta 7 (ITGB7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
交叉反应
- Chimpanzee, Baboon, Cynomolgus, 猕猴
-
纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
-
亚型
- IgG2a kappa
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Protect from prolonged exposure to light. Do not freeze.
-
储存条件
- 4 °C
-
储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
-
- Integrin beta 7 (ITGB7)
-
别名
- Integrin Beta7
-
背景
- Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
-
途径
- Integrin Complex
抗原
-