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IL-21 抗体 (PE)

IL21 适用: 人 FACS 宿主: 小鼠 Monoclonal 3A3-N2 PE
产品编号 ABIN2663779
发货至: 中国
  • 抗原 See all IL-21 (IL21) 抗体
    IL-21 (IL21) (Interleukin 21 (IL21))
    适用
    • 81
    • 29
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 68
    • 16
    • 5
    • 4
    • 1
    小鼠
    克隆类型
    • 80
    • 14
    单克隆
    标记
    • 50
    • 12
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-21 antibody is conjugated to PE
    应用范围
    • 69
    • 57
    • 13
    • 12
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    交叉反应
    猕猴
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    3A3-N2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL21 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    IL-21 (IL21) (Interleukin 21 (IL21))
    别名
    IL-21 (IL21 产品)
    别名
    IL-21 antibody, Za11 antibody, interleukin 21 antibody, IL21 antibody, Il21 antibody
    背景
    Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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