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IL-21 抗体 (PE)

This anti-IL-21 antibody is a 小鼠 单克隆 antibody detecting IL-21 in FACS. Suitable for 人.
产品编号 ABIN2663778
发货至: 中国

Quick Overview for IL-21 抗体 (PE) (ABIN2663778)

抗原

See all IL-21 (IL21) 抗体
IL-21 (IL21) (Interleukin 21 (IL21))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This IL-21 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

3A3-N2
  • 交叉反应

    猕猴

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    IL-21 (IL21) (Interleukin 21 (IL21))

    别名

    IL-21

    背景

    Interleukin 21 (IL-21) is a potent immunomodulatory cytokine mainly produced by NKT and CD4+ T-cells, particularly the inflammatory Th17 subset, and has pleiotropic effects on both innate and adaptive immune responses. These actions include positive effects such as enhancing proliferation of NK cells and cytotoxic T cells, and inhibitory effects on the antigen-presenting function of dendritic cells. It can also be proapoptotic for B cells and NK cells. Studies have shown that IL-21 is also an autocrine cytokine that potently induces Th17 differentiation, suppresses Foxp3 expression, and serves as a target for treating inflammatory diseases.

    途径

    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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