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OPRD1 抗体 (PE)

OPRD1 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal DOR7D2A4 PE
产品编号 ABIN2663677
发货至: 中国
  • 抗原 See all OPRD1 抗体
    OPRD1 (Opioid Receptor, delta 1 (OPRD1))
    适用
    • 62
    • 50
    • 49
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    宿主
    • 62
    • 1
    小鼠
    克隆类型
    • 53
    • 10
    单克隆
    标记
    • 27
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    • 2
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    This OPRD1 antibody is conjugated to PE
    应用范围
    • 50
    • 26
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    • 17
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    • 8
    • 4
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    DOR7D2A4
    亚型
    IgG2b kappa
    Top Product
    Discover our top product OPRD1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    OPRD1 (Opioid Receptor, delta 1 (OPRD1))
    别名
    delta Opioid Receptor (OPRD1 产品)
    别名
    OPRD antibody, DOR-1 antibody, Nbor antibody, mDOR antibody, opioid receptor delta 1 antibody, opioid receptor, delta 1 antibody, OPRD1 antibody, Oprd1 antibody
    背景
    Opioid receptors are the members of seven transmembrane G-protein coupled receptors. At least 3 types of opioid receptors, μ, κ, and δ, have been identified. Human δ-opioid receptor, know as OPRD, DOR, or hDOR, is primarily expressed in brain, especially in the areas of cortex, including olfactory bulb, hippocampus, and amygdale, as well as in basal ganglia and hypothalamus. Human OPRD gene has been mapped at chromosome 1p34.3-p36.1. The endogenous ligands for the OPRD are enkephalins. The third extracellular loop of the OPRD is critical for ligand binding. The ligands binding and signal transduction functions of δ-receptor can be synergized by forming heterodimers with κ-receptor. Activation of opioid receptor inhibits cAMP production, increases phosphodiesterase activity, and results in analgesia and convulsions. Recent studies have indicated that OPRD is involved in the mechanism of heroin dependence.
    途径
    Protein targeting to Nucleus
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