ICOS 抗体 (PE)
Quick Overview for ICOS 抗体 (PE) (ABIN2663297)
抗原
See all ICOS 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- The 7E.17G9 antibody reacts with the 47-57 kD ICOS protein, also known as inducible costimulatory molecule, and H4. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes and can costimulate T cells and induce proliferation. In addition ICOS has been shown to be involved in humoral immune responses (B cell germinal center formation). The ICOS ligand, B7h/B7RP-1 and B7-H2 is constitutively expressed in B cell areas of secondary lymphoid organs and can be induced in other tissues by LPS. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. ICOS stimulation has been shown to be involved in airway tolerance and the downregulation of pulmonary inflammation.
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纯化方法
- The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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亚型
- IgG2b kappa
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anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) antibody
ICOS 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 156-185) antibodyICOS 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) (Internal Region) antibodyVerified ICOS 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) antibodyICOS 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-200) antibodyICOS 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 1-199) antibodyICOS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) antibodyICOS 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 21-140) antibodyICOS 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) antibodyICOS 适用: 人 IHC, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal ISA-3 unconjugated
anti-Inducible T-Cell Co-Stimulator (ICOS) (AA 39-133) antibodyICOS 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- ICOS (Inducible T-Cell Co-Stimulator (ICOS))
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别名
- CD278
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途径
- Cancer Immune Checkpoints
抗原
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