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ICOS 抗体 (PE)

ICOS 适用: 小鼠 ELISA (Detection) 宿主: 仓鼠 Monoclonal 15F9 PE
产品编号 ABIN2663293
发货至: 中国
  • 抗原 See all ICOS 抗体
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    适用
    • 80
    • 23
    • 23
    • 6
    小鼠
    宿主
    • 70
    • 16
    • 2
    • 1
    仓鼠
    克隆类型
    • 68
    • 21
    单克隆
    标记
    • 37
    • 12
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This ICOS antibody is conjugated to PE
    应用范围
    • 59
    • 30
    • 28
    • 22
    • 14
    • 13
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 1
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    • 1
    ELISA (Detection)
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    15F9
    亚型
    IgG
    Top Product
    Discover our top product ICOS Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    ICOS (Inducible T-Cell Co-Stimulator (ICOS))
    别名
    CD278 (ICOS 产品)
    别名
    ICOS antibody, AILIM antibody, CCLP antibody, CRP-1 antibody, H4 antibody, Ly115 antibody, CD278 antibody, CVID1 antibody, Ailim antibody, inducible T-cell costimulator antibody, inducible T cell co-stimulator antibody, inducible T-cell co-stimulator antibody, ICOS antibody, LOC100232284 antibody, Icos antibody
    背景
    CD278 is a 47-57 kD protein, also known as inducible costimulatory molecule (ICOS), or H4. This protein is homologous to the CD28/CTLA-4 proteins. It forms homodimers and is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS has been shown to be involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. It has also been shown to be involved in airway tolerance and the downregulation of pulmonary inflammation.
    途径
    Cancer Immune Checkpoints
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