ZBTB16 抗体 (PE)
Quick Overview for ZBTB16 抗体 (PE) (ABIN2662834)
抗原
See all ZBTB16 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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亚型
- IgG
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anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (AA 1-220) antibody
ZBTB16 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (AA 381-480) antibodyZBTB16 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A7 unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (AA 381-480) antibodyZBTB16 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F10 unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) antibodyZBTB16 适用: 人 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 5B3 unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (AA 126-420) antibodyZBTB16 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (AA 381-480) antibodyZBTB16 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (Internal Region) antibodyZBTB16 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (C-Term) antibodyZBTB16 适用: 人, 小鼠, 大鼠, Bat, Cow, 犬, 豚鼠, 马, 猴, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) antibodyZBTB16 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 16 (ZBTB16) (AA 637-666) antibodyZBTB16 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.2 mg/mL
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))
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别名
- PLZF
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背景
- PLZF (promyelocytic leukemia zinc finger), also known as Zbtb16, Zinc finger and BTB domain-containing protein 16, Zfp145, is a member of the BTB-POZ family of transcription factors. It was first identified in a patient with acute promyelocytic leukemia, where a reciprocal chromosomal translocation t(11,17)(q23,q21) resulted in a fusion with RARA gene encoding retinoic acid receptor alpha. Expression of this transcriptional repressor in immune cells differs between human and mouse. In humans, PLZF is expressed in CD34+ progenitor cells and in primitive multipotent hematopoietic cell lines, NK cells, γ/δ T cells, CD4+ and CD8+ T cells. It is also expressed in MR1-specific mucosal-associated invariant T cells as well as in MHC class II-restricted T cells that develop via a thymocyte-thymocyte interaction. PLZF is involved in NK cell function, cellular quiescence, and growth suppression. It also inhibits gene expression induced by retinoic acid receptor. In mice, PLZF is highly expressed in immature CD1d-resricted invariant NKT (iNKT) cells, a subset of γ/δ (Vg1.1+Vd6.3+) T cells, and non-invariant CD1d-restricted T cells. PLZF exists as a homodimer or in complex with PLZP, and has been shown to be involved in the development of NKT cells. It is also reported to be expressed in embryonic tissues, giving rise to hematopoietic progenitors.
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途径
- Positive Regulation of fat Cell Differentiation
抗原
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