NOTCH4 抗体 (PE)
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北京 101111
Quick Overview for NOTCH4 抗体 (PE) (ABIN2662819)
抗原
See all NOTCH4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
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亚型
- IgG1 kappa
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anti-Notch 4 (NOTCH4) (AA 1715-2001) antibody
NOTCH4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Middle Region) antibodyNOTCH4 适用: 人, 大鼠, Cow, 马, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) antibodyNOTCH4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 371-420) antibodyNOTCH4 适用: 人, Cow, 马, 豚鼠, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1824-2003) antibodyNOTCH4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1261-1273) antibodyVerified NOTCH4 适用: 人, 小鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (Middle Region) antibodyNOTCH4 适用: 人, Cow, 马, 豚鼠, Pig, 犬, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (C-Term), (cleaved) antibodyNOTCH4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Notch 4 (NOTCH4) (AA 1819-1851), (C-Term) antibodyNOTCH4 适用: 人 WB 宿主: 兔 Polyclonal RB52895 unconjugated
anti-Notch 4 (NOTCH4) antibodyNOTCH4 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from prolonged exposure to light. Do not freeze.
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储存条件
- 4 °C
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储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- NOTCH4 (Notch 4 (NOTCH4))
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别名
- Notch 4
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背景
- Neurogenic locus notch homolog protein 4 (Notch 4) is a transmembrane heterodimer in which the extracellular domain contains 29 EGF repeats and 3 LNR repeats. The intracellular domain contains 5 ANK repeats, 1 PEST motif, and 1 RAM23 domain. Notch 4 controls many developmental processes in the cell such as differentiation, proliferation, and apoptosis. In addition, it also plays a role in vascular, renal, and hepatic development. Notch 4 is expressed by a variety of tissues such as heart, lung, placenta, liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow, and fetal liver. The Notch 4 ligands are Jagged1, Jagged2, Delta1, Delta3 and Delta4. After ligand binding, Notch 4 is cleaved by the TNF-α converting enzyme (TACE). The extracellular domain remains on the cell surface while the intracellular domain is released and translocated to the nucleus where it binds to CBF-1, leading to the expression of genes of the Hairy/Enhancer of Split (HES) and HES-related repressor protein (HERP) families.
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途径
- Notch Signaling
抗原
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