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CXCL9 抗体 (PE)

This anti-CXCL9 antibody is a 小鼠 单克隆 antibody detecting CXCL9 in FACS. Suitable for 人.
产品编号 ABIN2662706
发货至: 中国

Quick Overview for CXCL9 抗体 (PE) (ABIN2662706)

抗原

See all CXCL9 抗体
CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

适用

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宿主

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小鼠

克隆类型

  • 71
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单克隆

标记

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This CXCL9 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

J1015E10
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CXCL9 (gamma-Interferon-Induced Monokine (CXCL9))

    别名

    CXCL9

    背景

    Chemokine (C-X-C motif) ligand 9 (CXCL9), also known as monokine induced by gamma interferon (MIG), is a small cytokine belonging to the non-ELR (lacking a Glu-Leu-Arg motif in the N-terminal region) motif CXC chemokines. CXCL9 is one of the ligands to share its receptor, CXCR3, with other two CXC chemokine family members, CXCL10 and CXCL11, through different binding fashions. The rank order of binding affinity is CXCL11>CXCL10>CXCL9. Some studies have revealed that these ligands have redundant functions in vivo, other studies have demonstrated that the three CXCR3 ligands can collaborate and even compete with each other. CXCL9 is mainly produced by activated macrophages and some cancer cells. Functioning as a chemoattractant, CXCL9 attracts CXCR3-expressing cells (such as a subset of circulating T cells, B cells, and natural killer cells) into inflammatory sites. Like other chemokines, CXCL9 is also able to elicit intracellular calcium flux and activate PI3K and MAPK. It participates in multiple immune and inflammatory responses by affecting cell growth, movement, or activation.
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