电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CD41, CD61 抗体 (PE)

This anti-CD41, CD61 antibody is a 小鼠 单克隆 antibody detecting CD41, CD61 in FACS. Suitable for 人.
产品编号 ABIN2662642
发货至: 中国

Quick Overview for CD41, CD61 抗体 (PE) (ABIN2662642)

抗原

See all CD41, CD61 抗体
CD41, CD61 (CD41,CD61)

适用

  • 12
  • 7
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2

宿主

  • 22
小鼠

克隆类型

  • 22
单克隆

标记

  • 12
  • 4
  • 4
  • 1
  • 1
This CD41, CD61 antibody is conjugated to PE

应用范围

  • 18
  • 10
  • 5
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
Flow Cytometry (FACS)

克隆位点

A2A9-6
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD41, CD61 (CD41,CD61)

    别名

    CD41/CD61

    背景

    CD41/CD61, also known as gpIIb/IIIa, is a member of a family integrin receptors. This is a complex comprised by CD41 and CD61 through non-covalent association. CD41/CD61 is mainly expressed by platelets and megakaryocytes. The resting form of the CD41/CD61 complex is involved in platelet activation and aggregation by binding to immobilized fibrinogen. After activation, CD41/CD61 becomes a receptor for soluble fibrinogen and several other RGD-containing adhesive proteins such as von Willebrand Factor (vWF) and fibronectin. An absence or dysfunction of CD41/CD61 on the platelet surface results in an inherited bleeding disorder, called Glanzmann Thromsasthenia (GT). CD41/CD61 has been found on murine hematopoietic progenitor cells, indicating that this complex may play a role in regulating hematopoietic development.
You are here:
Chat with us!