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- 抗原 See all CLEC7A 抗体
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CLEC7A antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- 克隆位点
- 15E2
- 亚型
- IgG2a kappa
- Top Product
- Discover our top product CLEC7A Primary Antibody
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anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 66-247) antibody
CLEC7A 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 4G2G6 unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 41-140) antibodyCLEC7A 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 1-44) antibodyCLEC7A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibodyCLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal BD6 unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibodyCLEC7A 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal 15E2 unconjugated
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibody (APC)CLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal 15E2 APC
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) antibody (PE)CLEC7A 适用: 人 FACS 宿主: 小鼠 Monoclonal 15E2 PE
anti-C-Type Lectin Domain Family 7, Member A (CLEC7A) (AA 36-127) antibodyCLEC7A 适用: 人, 猴 ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from prolonged exposure to light. Do not freeze.
- 储存条件
- 4 °C
- 储存方法
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- 抗原
- CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))
- 别名
- CD369 (CLEC7A 产品)
- 背景
- CD369 (Dectin-1), also known as CLEC7A and beta-glucan receptor (BGR), is a 33 kD type II transmembrane C-type lectin. It consists of a C-terminal stalk with a carbohydrate recognition domain (CRD) in the extracellular domain, a transmembrane segment, and a short N-terminal ITAM containing a cytoplasmic tail. CLEC7A is predominantly expressed on dendritic cells. Subsequent work has shown expression on B cells, monocytes, eosinophils, mast cells, macrophages, endothelial cells, and low expression on some subsets of T cells. CLEC7A lacks residues involved in calcium ligation that mediates carbohydrate-binding by classical C-type lectins. CLEC7A functions as a receptor to mediate innate immunity to fungal pathogens by selectively binding beta-glucan polymers, a major component of yeast and mycobacterial cell walls.
- 途径
- Activation of Innate immune Response
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