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CCRL1 抗体 (PE)

CCRL1 适用: 人 FACS 宿主: 小鼠 Monoclonal 13E11 PE
产品编号 ABIN2662412
发货至: 中国
  • 抗原 See all CCRL1 抗体
    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
    适用
    • 16
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 15
    • 1
    小鼠
    克隆类型
    • 16
    单克隆
    标记
    • 16
    This CCRL1 antibody is conjugated to PE
    应用范围
    • 13
    • 9
    • 8
    • 3
    • 3
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    克隆位点
    13E11
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CCRL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))
    别名
    CCX-CKR (CCRL1 产品)
    别名
    CC-CKR-11 antibody, CCBP2 antibody, CCR-11 antibody, CCR10 antibody, CCR11 antibody, CCRL1 antibody, CCX CKR antibody, CCX-CKR antibody, CKR-11 antibody, PPR1 antibody, VSHK1 antibody, A630091E18Rik antibody, CCX-CKR1 antibody, Ccrl1 antibody, Cmkbrl1 antibody, atypical chemokine receptor 4 antibody, chemokine (C-C motif) receptor-like 1 antibody, Chemokine receptor-like 1 antibody, chemerin chemokine-like receptor 1 antibody, ACKR4 antibody, Ackr4 antibody, CCRL1 antibody, cml1 antibody, CMKLR1 antibody
    背景
    Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seven transmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding by CCX-CKR causes its internalization, reducing levels of available chemokine, and thus regulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromal cells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). A low CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancer patients.
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