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CCRL1 抗体 (PE)

This anti-CCRL1 antibody is a 小鼠 单克隆 antibody detecting CCRL1 in FACS. Suitable for 人.
产品编号 ABIN2662412
发货至: 中国

Quick Overview for CCRL1 抗体 (PE) (ABIN2662412)

抗原

See all CCRL1 抗体
CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))

适用

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宿主

  • 16
  • 2
小鼠

克隆类型

  • 18
单克隆

标记

  • 18
This CCRL1 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

13E11
  • 纯化方法

    The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    亚型

    IgG2b kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CCRL1 (Chemokine (C-C Motif) Receptor-Like 1 (CCRL1))

    别名

    CCX-CKR

    背景

    Human CCX-CKR, also known as CCRL1, is a 40 kD, G-protein-coupled, seven transmembrane receptor. CCRL1 is a decoy receptor for CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25 that regulates chemotaxis of lymphocytes and cancer cells. Chemokine binding by CCX-CKR causes its internalization, reducing levels of available chemokine, and thus regulating migration of lymphocytes and cancerous cells. CCX-CKR is expressed by stromal cells of skin-draining lymph nodes, thymic epithelial cells, and immature dendritic cells (DCs). A low CCX-CKR expression in tumor cells correlates with a poor survival rate of breast cancer patients.
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