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Endoglin 抗体 (Pacific Blue)

This anti-Endoglin antibody is a 大鼠 单克隆 antibody detecting Endoglin in FACS. Suitable for 小鼠.
产品编号 ABIN2662188
发货至: 中国

Quick Overview for Endoglin 抗体 (Pacific Blue) (ABIN2662188)

抗原

See all Endoglin (ENG) 抗体
Endoglin (ENG)

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This Endoglin antibody is conjugated to Pacific Blue

应用范围

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Flow Cytometry (FACS)

克隆位点

MJ7-18
  • 纯化方法

    The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from prolonged exposure to light. Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Endoglin (ENG)

    别名

    CD105

    背景

    CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.
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