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NGFR 抗体 (FITC)

NGFR 适用: 人 WB, FACS, IF, IHC, ICC, IP, ICFC 宿主: 小鼠 Monoclonal ME20-4 FITC
产品编号 ABIN2661631
发货至: 中国
  • 抗原 See all NGFR 抗体
    NGFR (Nerve Growth Factor Receptor (NGFR))
    适用
    • 156
    • 66
    • 58
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    宿主
    • 88
    • 75
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    小鼠
    克隆类型
    • 93
    • 75
    单克隆
    标记
    • 85
    • 14
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    This NGFR antibody is conjugated to FITC
    应用范围
    • 92
    • 82
    • 57
    • 48
    • 40
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    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Intracellular Flow Cytometry (ICFC)
    交叉反应
    猴, Raccoon (Procyon lotor), 绵羊, 猫, 犬, 猪, 兔
    纯化方法
    The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
    克隆位点
    ME20-4
    亚型
    IgG1 kappa
    Top Product
    Discover our top product NGFR Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from prolonged exposure to light. Do not freeze.
    储存条件
    4 °C
    储存方法
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原
    NGFR (Nerve Growth Factor Receptor (NGFR))
    别名
    CD271 (NGFR 产品)
    背景
    CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
    途径
    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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