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Integrin beta 7 抗体 (Biotin)

This anti-Integrin beta 7 antibody is a 大鼠 单克隆 antibody detecting Integrin beta 7 in FACS. Suitable for 人 和 小鼠.
产品编号 ABIN2661247
发货至: 中国

Quick Overview for Integrin beta 7 抗体 (Biotin) (ABIN2661247)

抗原

See all Integrin beta 7 (ITGB7) 抗体
Integrin beta 7 (ITGB7)

适用

  • 70
  • 23
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 51
  • 12
  • 7
  • 4
  • 1
大鼠

克隆类型

  • 52
  • 21
  • 2
单克隆

标记

  • 37
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Integrin beta 7 antibody is conjugated to Biotin

应用范围

  • 41
  • 22
  • 22
  • 13
  • 13
  • 8
  • 7
  • 7
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

FIB504
  • 交叉反应

    Chimpanzee, Baboon, Cynomolgus, 猕猴

    纯化方法

    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

    亚型

    IgG2a kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    Integrin beta 7 (ITGB7)

    别名

    Integrin Beta7

    背景

    Integrin β7 is a 130 kD glycoprotein also known as integin βp. It is a member of the Ig superfamily. In association with integrin α4 or αE chain, β7 forms α4/β7 or αE/β7 heterodimer. α4/β7 (CD49d/β7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. αE/β7 (CD103/β7,αIEL/β7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/β7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.

    途径

    Integrin Complex
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